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Hyperbaric Oxygen Therapy for Avascular Necrosis

Updated: Mar 23

Hyperbaric Oxygen Therapy (HBOT) has been investigated as a potential treatment for Avascular Necrosis (AVN), a condition characterized by the death of bone tissue due to a lack of blood supply. AVN can lead to pain, reduced mobility, and eventual joint destruction if left untreated. This article explores how HBOT can be beneficial for patients with AVN, supported by scientific findings and clinical observations.

Understanding Avascular Necrosis

Avascular Necrosis, also known as osteonecrosis, primarily affects the joints at the shoulder, knee, and hip. The condition can be caused by a range of factors, including trauma, steroid use, excessive alcohol consumption, and certain medical conditions. The loss of blood flow to the bone leads to the death of bone cells and can significantly impact a person's quality of life due to pain and loss of joint function.

The Role of Hyperbaric Oxygen Therapy in Treating AVN

HBOT involves breathing pure oxygen in a pressurized environment, which can significantly increase the amount of oxygen dissolved in the blood. This oxygen-rich blood can then reach areas of the body that are receiving poor blood flow, such as the areas affected by AVN.

  1. Promoting Bone Healing: HBOT can stimulate the formation of new blood vessels (angiogenesis) in and around the affected bone, improving blood supply and potentially reversing or halting the progression of AVN. Increased oxygen levels can also enhance the ability of bone cells to repair and regenerate, promoting the healing process.

  2. Reducing Inflammation: The therapy has anti-inflammatory properties, which can reduce swelling and pain in the affected area, providing symptomatic relief to patients.

  3. Preventing Further Damage: By improving oxygenation and blood flow to the affected bone, HBOT can help prevent further bone damage and reduce the risk of joint collapse, a common complication of AVN that often requires surgical intervention.

Evidence Supporting HBOT for AVN

Several studies and clinical trials have explored the efficacy of HBOT for AVN. For instance:

  • A study published in the "Undersea and Hyperbaric Medicine Journal" reported positive outcomes in patients with early-stage AVN, indicating that HBOT can halt the progression of the disease and improve symptoms.

  • Research presented in the "Journal of Rheumatology" highlighted HBOT's role in reducing the need for surgical intervention in patients with AVN of the hip, suggesting it as a potential conservative treatment option.

Clinical Considerations and Safety

While HBOT is generally safe, it's essential for treatment to be conducted under the guidance of a medical professional experienced in hyperbaric medicine. Potential risks and side effects, such as ear pressure changes or oxygen toxicity, should be discussed before starting therapy.


Hyperbaric Oxygen Therapy offers a promising treatment option for Avascular Necrosis, with the potential to improve blood supply, reduce symptoms, and prevent further joint damage. Although more research is needed to fully establish its role in the management of AVN, current evidence suggests that HBOT could serve as a valuable adjunct to traditional treatment modalities, offering hope to patients seeking to avoid surgery and improve their quality of life.

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